… observe in 5-HT1A autoreceptor function suggest that different adaptive mechanisms are
recruited in … are needed to understand the generation of sex dependent differences in behavior. …

… These mice exhibited increased 5-HT1A autoreceptor levels and function, consistent with …
Interestingly, female MeCP2-cKO mice displayed reduced anxiety, while males showed …

… an inducible conditional HTR1A KO mouse (1AcKO) to excise … the 1AcKO mice had no
significant change in baseline anxiety- … Sex-dependent anxiety and depression phenotypes have …

… , the serotonin 1A (5-HT 1A ) receptor. … 1A autoreceptors and led to a sex-dependent
behavioural phenotype: females had reduced anxiety, whereas males showed increased anxiety …

… the changes in 5-HT 1A autoreceptor in the midbrain of stress-adaptive and -unadaptive mice
in … Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene …

… The extent of up-regulation of 5-HT1A autoreceptors in the latter model may overwhelm
endogenous sex-dependent differences to result in SSRI-resistant anxiety and depression. …

… of serotonin-1A (5-HT1A) autoreceptors, which negatively regulate 5-HT tone. To test the role
of Freud-1 in vivo, we generated mice … In cF1ko mice, 5-HT1A autoreceptor protein, binding …

… 5-HT1A autoreceptor function with no change in receptor levels.Mouse genetic models
with … This nongenetic maternal transmission of anxiety to wild-type mice appears to involve …

… by an increase in 5-HT1A autoreceptors may contribute to resistance to SSRI treatment.
To address the role of 5-HT1A autoreceptors in antidepressant response, we conditionally …

… function, we assessed transcriptomic changes in the hippocampus of … Sex-dependent
adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice …